Fig. 3

Overview of the web interface. My Personal Mutanome has an all-in-one interface that allows users to search (a), view results (b, c), and visualize nodetic/edgetic mutations (Figs. 4 and 5) in the same web page, improving the smoothness in navigating through the database and removing the needs for switching between browser tabs. Users can use both UniProt ID and gene symbol to search for a protein or a specific PPI (a), which loads the basic information page (b). These pages provide an overview of the data that are available for the proteins, PPIs, mutations, and functional site in My Personal Mutanome. (c) Additional information such as all the mapped mutations for a specific PPI can be loaded on user request. Survival and drug responses are found by loading the “Edgetic” and the “Pharmacogenomics” information on the PPI and functional site pages. By clicking the buttons, users can browse through all the related information progressively