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Fig. 5 | Genome Biology

Fig. 5

From: Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Fig. 5

a Fold change difference in fraction of CpG regions (three or more consecutive significantly allelically differentially methylated CpGs) in ChromHMM-assigned state versus the fraction of single significantly allelically differentially methylated CpGs in the same ChromHMM state. The x-axis lists the eight ChromHMM states and each colored bar shows a different cell type/methylation interrogation technology. b Proportion of correlations tested in each ChromHMM state with CpG methylation sequenced by WGBS and MCC-Seq. c Fold-enrichment of positively correlated CpGs evaluated by MCC-Seq in each ChromHMM state. d Fold-enrichment of positive WGBS correlations. e Fold-enrichment of negatively correlated MCC-Seq CpGs per state. f Fold-enrichment of negatively correlated WGBS CpGs per state

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