Fig. 5

Rates of DNA cleavage with various SGN concentrations. A set of SGN (0, 0.13, 0.25, 0.37, 0.50, 0.62, 1.0, and 2.0 nM) was used to cleave S-8 at a fixed concentration (100 nM). The rates (v) for the cleavage, determined from the generation of the product (P) over time (t), were plotted versus the corresponding SGN concentrations. The rates were fitted into a red curve with the equation of y = 2.9684 x ^1.9255 before reaching a plateau. The black dotted curve linked the average rates of reactions under different concentrations of SGN