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Table 1 Increased nucleolar association of chromosomes expressing transgenic XIST

From: Impact of flanking chromosomal sequences on localization and silencing by the human non-coding RNA XIST

Integration site

% perinuclear

% perinuclear

% perinuclear

% perinucleolar

% perinucleolar

% perinucleolar

No DOX

DOX

CHANGE

No DOX

DOX

CHANGE

1p

27

34

7

10

36

16a

3q

78

70

−8

10

18

8

4q

57

74

17b

12

25

14a

7p

32

27

−5

29

47

18a

7q

30

53

23a

28

39

11c

8p

59

39

−21a

29

56

27a

12q

36

39

3

18

35

17a

15q

24

36

14c

46

53

7

Xq23

42

46

5

31

41

10

  1. The numbers shown are based on three independent experiments for the DOX results and one experiment for the No DOX results, with ≥50 cells counted for each integration site in each experiment. Chi-squared test (a P ≤0.001; b P ≤0.01; c P ≤0.05)