Fig. 3
From: Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data
Cell-type-specific A/B compartments using Hi-C data are predicted using DNA methylation data. The figure displays data on all of chromosome 14 at 100-kb resolution. a The first eigenvector of the HiC-EBV-2014 dataset. b The smoothed first eigenvector of the binned correlation matrix of the 450 k-EBV dataset. c The first eigenvector of the HiC-IMR90-2014 Hi-C dataset. d The smoothed first eigenvector of the binned correlation matrix of the 450 k-fibroblast dataset. e The difference between (a) and (c). f the difference between (b) and (d). The high correlation between (e) and (f) supports that the correlation eigenvectors of the 450 k data can be used to find differences between compartments in the two cell types