Fig. 1
From: Getting the genome in shape: the formation of loops, domains and compartments
Cell-to-cell variability in genomic neighborhoods. The upper half shows a simplified overview of chromatin behavior during the cell cycle. Chromosome territory positioning differs between mother cell and daughter cells (but can be fairly similar between two daughter cells owing to symmetric spindle positioning). In the lower half, the zoom view schematically shows the high levels of variation between the genomic neighborhoods of a given topologically associating domain (TAD) of interest (indicated in blue) across the mother cell and the two daughter cells 1 and 2. TADs are represented by colored spheres