Table 1 Manual classification of cases of domain atrophy
From: Domain atrophy creates rare cases of functional partial protein domains
| Â | Â | N-terminal end-bounded atrophy | C-terminal end-bounded atrophy | Upstream domain-bounded atrophy | Downstream domain-bounded atrophy | Within-domain atrophy |
|---|---|---|---|---|---|---|
| Â | Total | 499 (100%) | 468 (100%) | 125 (100%) | 331 (100%) | 213 (100%) |
Structure available | True domain atrophy | 6 (1.20%) | 0 (0.00%) | 0 (0.00%) | 2 (0.60%) | 0 (0.00%) |
False positive | 161 (32.26%) | 119 (25.42%) | 27 (21.60%) | 104 (31.41%) | 45 (21.13%) | |
Homologous structure available | Putative domain atrophy | 34 (6.81%) | 26 (5.55%) | 0 (0.00%) | 3 (0.90%) | 4 (1.88%) |
False positive | 216 (43.28%) | 218 (46.58%) | 91 (72.80%) | 207 (62.53%) | 99 (46.48%) | |
No structure available | Unknown | 82 (16.43%) | 105 (22.43%) | 7 (5.60%) | 15 (4.53%) | 65 (30.52%) |