A depauperate immune repertoire precedes evolution of sociality in bees

Table 7 Genes under positive selection (using FDR < 0.05) on the branch to Bombus (5 taxa tree)

OrthoDB group id ^a	Gene ^b	Classification	Total sites ^c	Likelihood ratio ^d	p-value	BH-corrected q-value ^e	Positively selected sites ^f
EOG666T1W	domeless	JAK/STAT pathway	1435	9.552	0.00100	0.01951	24L, 102R, 224S, 526A, 770T, 799N, 838V, 942V, 952I, 954A, 959L, 960A, 992Q, 1055R, 1056W, 1312T, 1316D
EOG6VDNFR	dorsal	Relish	353	22.813	0.00000	0.00013	104Q, 177S, 309R, 316K, 317I, 318S, 332S, 333Y, 334N, 336S, 347N, 350R
EOG66Q57J	LOC100642902 (B. terr)	Serine protease inhibitor	1189	20.354	0.00000	0.00023	165S, 230D, 247P, 419T, 500S, 502D, 590Q, 617S
EOG6BG7B9	snmp1	Scavenger receptor	430	18.183	0.00001	0.00047	77G, 217G, 227K, 346L, 353K, 394N, 395K
EOG6VX0M3	ark	Caspase	1128	7.406	0.00325	0.04167	156L, 668S, 992R, 1074N, 1079L
EOG6ZPC9T	rm62-F	Small RNA regulatory pathway members	545	11.406	0.00037	0.01032	120R, 136G, 169Q, 542N, 543K
EOG6RV16R-1	BGRP-1	GNBP	459	9.363	0.00111	0.01951	222R, 229E, 370P, 458W
EOG6X0K8Q	myd88	Toll pathway	209	9.782	0.00088	0.01951	45E, 83F, 133P, 199D
EOG6Z8WBN	catalase	Catalase	181	7.431	0.00321	0.04167	53A, 83T, 89S
EOG6931ZS-1	TLR-7	Toll receptor	1299	12.107	0.00025	0.00886	230T, 1190K, 1191D
EOG6KKWHX	argonaute-2	Small RNA regulatory pathway members	810	8.276	0.00201	0.03147	684A

^aGroup identifiers are from OrthoDB 6 (http://cegg.unige.ch/orthodb6).
^bNumber of codons remaining in the alignment after trimming with Gblocks.
^cComparison of Branch-site model A versus a constrained version with ω ₂ = 1.
^eMultiple test correction by the method of Benjamini and Hochberg to control the false discovery rate (only groups where FDR < 0.05 are shown).
^fSites are classified as under positive selection if the Bayesian posterior probability > 0.75 (> 0.95 in bold). The reference sequence is from A. mellifera.

ISSN: 1474-760X