Figure 6
From: Global loss of DNA methylation uncovers intronic enhancers in genes showing expression changes
Identifcation and characterization of de-regulated genes. (A) The 1,640 genes significantly differentially expressed between HCT116 and DKO1 cells are shown in red (P-value <0.05, fold-change >1.2). (B) Gene Ontology results for down-regulated genes; up-regulated genes were not enriched for any Gene Ontology terms. (C) The epigenetic profiles at the promoters of genes up-regulated (right panel) and down-regulated in DKO1 (left panel).