Figure 1
From: Methylome analysis identifies a Wilms tumor epigenetic biomarker detectable in blood
Identification of differentially methylated loci with genome-wide significance. Manhattan plot showing –log10 p-values for all CpGs (462,537) generated by linear modelling of normal kidney (NK) against Wilms tumour (WT). CpGs with genome-wide significance (n = 309) appear above the red line. DMRs 1 and 2 on chromosome 6 and DMR-3 on chromosome 11 are shown in green.