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Figure 3 | Genome Biology

Figure 3

From: Genetic factors underlying discordance in chromatin accessibility between monozygotic twins

Figure 3

Effect of chromatin discordance and somatic mutation on differential expression. (A) Within-pair differential expression according to proximal chromatin accessibility. (B) The statistical significance of a rank correlation between high, medium, and low magnitudes of chromatin discordance and high, medium, and low levels of differential gene expression, as assessed based on 10,000 permutations of differential expression and chromatin discordance. (C) Differential expression according to genes with broken TF motifs and relevant ChIP evidence compared with all genes as control.

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