Figure 7

Promoter cis -regulatory sequences affect local H3.3 incorporation. (A-C) Metagene plots of H3.3 signals across gene bodies (blue bar) between -3 kb and +3 kb for genes with promoters that carry TATA elements (A), GA elements (B) or neither TATA nor GA elements (coreless) (C). Genes were first grouped according to transcript abundance, and genes with promoters of each type are presented separately. (B) H3.3 signals at promoters with GA elements (red) or promoters of the top 25% most strongly expressed genes (blue).