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Figure 7 | Genome Biology

Figure 7

From: The non-coding snRNA 7SKcontrols transcriptional termination, poising, and bidirectionality in embryonic stem cells

Figure 7

The non-coding RNA (ncRNA) 7SK has a central role in controlling transcription in embryonic stem cells. 7SK is required for the repression of genes that are silent or expressed at a low level. Widespread failed transcriptional termination was also seen after 7SK knockdown. 7SK is a major regulator of transcriptional directionality, by preventing the transcription of upstream divergent RNAs (udRNAs).

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Genome Biology

ISSN: 1474-760X

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