Figure 3

Differential gene expression across the H. contortus lifecycle. (a) Numbers of genes significantly up-regulated (red) and down-regulated (blue) between life-stages. (b) The expression profiles of genes determined to be differentially expressed between any pair of stages are shown in clusters ordered by the stage at which they are most highly expressed. The innermost circle shows normalized expression levels during the egg stage with further concentric circles showing expression in the L1, L3, L4 stages, followed by male worms, female worms and then female gut samples. Mean expression values were taken over three replicates and are shown on a log2 scale.