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Figure 2 | Genome Biology

Figure 2

From: PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs

Figure 2

Performance of PROmiRNA on intronic and intergenic data set. (a) The fraction of predicted highly expressed CAGE tag clusters versus lowly expressed tag clusters in intronic miRNA regions at varying probability cutoffs. (b) The percentage of PROmiRNA predictions in intronic regions upstream of annotated miRNAs (upstream regions) versus the percentage of predictions in intronic regions downstream of miRNAs (downstream regions) at different probability cutoffs. (c) The percentage of bases covered by predictions in random intronic regions versus the probability threshold for both PROmiRNA and S-Peaker. (d) The percentage of bases covered by predictions in random intergenic regions versus the probability threshold for both PROmiRNA and S-Peaker. (e) The percentage of Barski miRNA promoters (positive regions) versus the percentage of negative regions hit by predictions at different probability cutoffs for both PROmiRNA and S-Peaker.

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