From: A blood based 12-miRNA signature of Alzheimer disease patients
Comparison | Classification | Permutation test | ||||
---|---|---|---|---|---|---|
 | Acc | Spec | Sens | Acc | Spec | Sens |
AD vs. control | 93.3% ± 4.6 CI:92.4-94.2% | 95.1% ± 5.4 CI:94.1-96.2% | 91.5% ± 5.8 CI:90.4-92.7% | 50.7% ± 12.5 CI:48.2-53.1% | 50.7% ± 13.3 CI:48.1-53.3% | 50.7% ± 14.1 CI:47.9-53.4% |
MCI vs. control | 84.2% ± 3.7 CI:83.4-84.9% | 81.1% ± 5.6 CI:80.0-82.2% | 87.7% ± 3.7 CI:87.0-88.5% | 51.3% ± 11.4 CI:49.0-53.5% | 52.0% ± 12.2 CI:50.0-54.4% | 50.4% ± 13.5 CI:47.8-53.1% |
PSY vs. control | 97.1% ± 1.6 CI:96.8-97.4% | 95.3% ± 1.7 CI:95.0-95.6% | 99.0% ± 2.4 CI:98.5-99.4% | 48.7% ± 10.6 CI:46.7-50.8% | 48.5% ± 12.4 CI:46.0-50.9% | 49.0% ± 12.1 CI:46.6-50.8% |
Other ND vs. control | 82.8% ± 5.0 CI:81.8-83.7% | 84.0% ± 5.8 CI:83.0-85.2% | 81.4% ± 6.7 CI:80.1-82.7% | 50.3% ± 10.3 CI:48.3-52.3% | 50.7% ± 11.7 CI:48.4-53.0% | 50.0% ± 12.0 CI:47.6-52.3% |
NEURO vs. control | 86.1% ± 5.7 CI:85.0-87.2% | 88.7% ± 6.8 CI:87.3-90.0% | 83.6% ± 6.6 CI:82.3-84.9% | 49.9% ± 10.8 CI:47.8-52.1% | 50.1% ± 11.5 CI:47.9-52.3% | 49.8% ± 13.3 CI:47.2-52.3% |
AD vs. MCI | 75.6% ± 7.8 CI:74.1-77.2% | 76.7% ± 8.3 CI:75.1-78.4% | 74.6% ± 9.7 CI:72.7-76.5% | 50.6% ± 9.4 CI:48.7-52.4% | 51.2% ± 10.4 CI:49.1-53.2% | 49.9% ± 11.7 CI:47.7-52.2% |
AD vs. PSY | 77.8% ± 4.0 CI:77.0-78.5% | 76.3% ± 4.8 CI:75.4-77.3% | 79.2% ± 5.4 CI:78.1-80.2% | 50.0% ± 8.0 CI:48.5-51.6% | 49.1% ± 9.3 CI:47.3-50.9% | 51.1% ± 10.3 CI:49.1-53.1 |
AD vs. other ND | 73.8% ± 4.4 CI:72.9-74.7% | 75.2% ± 4.7 CI:74.2-76.1% | 72.4% ± 6.4 CI:71.2-73.7% | 50.1% ± 7.3 CI:48.7-51.5% | 49.2% ± 9.4 CI:47.4-51.1% | 51.0% ± 8.5 CI:49.3-52.7% |