Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance

Table 2 Ontology enrichment analysis of age-associated differentially methylated probes

GO term	Description	Adjusted P-value
GO:0000904	Cell morphogenesis involved in differentiation	0.0035
GO:0051056	Regulation of small GTPase-mediated signal transduction	0.0042
GO:0046578	Regulation of Ras protein signal transduction	0.0075
GO:0030182	Neuron differentiation	0.0157
GO:0031175	Neuron projection development	0.0192
GO:0048667	Cell morphogenesis involved in neuron development	0.022
GO: 0007409	Axonogenesis	0.026
GO:0048812	Neuron projection morphogenesis	0.027
GO:0000902	Cell morphogenesis	0.038

Gene Ontology (GO) terms significant at an adjusted P-value <0.05 [81] are shown. For full analysis, see Table S2 in Additional file 2.

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