Transcriptome and proteome quantification of a tumor model provides novel insights into post‐transcriptional gene regulation

Table 3 Biological pathways exhibiting significant alterations in post‐transcriptional regulation

Kyoto Encyclopedia of Genes and Genomes pathway	Correlation ρ	Significance^a
Metabolism
Energy metabolism	0.23	***
Lipid metabolism	0.49	*
Nucleotide metabolism	0.75	*
Genetic information processing
Transcription	0.16	***
Translation	0.45	***
Folding, sorting and degradation	0.46	***
Cellular processes
Transport and catabolism	0.39	***

^aDifferent biological pathways show considerable variability in their correlation of transcript‐to‐protein level changes. The statistical significance of the deviation from the global correlation (ρ=0.61) was estimated by random sampling, controlling for the number of quantified proteins in each pathway (* P<0.05; ** P<0.01; *** P<0.001).

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