Single-cell genomics reveal low recombination frequencies in freshwater bacteria of the SAR11 clade

Table 2 Functional categories of protein clusters inferred to have been gained and lost in the LD12 clade

Information storage and processing		Gains	Losses
A	RNA processing and modification	0	0
J	Translation, ribosomal structure and biogenesis	1	2
K	Transcription	5	0
B	Chromatin structure and dynamics	0	1
L	Replication, recombination and repair	7	2
	Total	13	5
Metabolism
H	Coenzyme transport and metabolism	2	0
F	Nucleotide transport and metabolism	0	2
Q	Secondary metabolites biosynthesis, transport and catabolism	11	9
C	Energy production and conversion	8	8
P	Inorganic ion transport and metabolism	9	16
I	Lipid transport and metabolism	4	5
G	Carbohydrate transport and metabolism	12	12
E	Amino acid transport and metabolism	23	22
	Total	69	74
Cellular processes and signaling
O	Posttranslational modification, protein turnover, chaperones	5	7
W	Extracellular structures	0	0
T	Signal transduction mechanisms	5	4
N	Cell motility	2	1
Y	Nuclear structure	0	0
V	Defense mechanisms	3	1
Z	Cytoskeleton	0	0
M	Cell wall/membrane/envelope biogenesis	22	6
D	Cell cycle control, cell division, chromosome partitioning	0	0
U	Intracellular trafficking, secretion, and vesicular transport	3	1
	Total	40	20
Poorly characterized
S	Function unknown	15	14
R	General function prediction only	26	31
	Total	41	45
Unmapped to the COG database		103	17
Mapped to the COG database		135	113

ISSN: 1474-760X