Table 1 Mutations that reduce growth control by pHc
Category | Gene | ORF | Absolute pHca | GO process |
|---|---|---|---|---|
Inositol polyphosphates | PLC1 | YPL268W | 6.92 (0.035) | Inositol phosphate biosynthetic process |
| Â | KCS1 | YDR017C | 6.76 (0.047) | Inositol phosphate biosynthetic process |
Signal transduction | LCB5 | YLR260W | 6.99 (0.034) | Calcium-mediated signaling |
| Â | RHO5 | YNL180C | 7.02 (0.025) | Rho protein signal transduction |
Lipid synthesis | CAX4 | YGR036C | 6.93 (0.057) | Lipid biosynthetic process |
| Â | PDX3 | YBR035C | 6.99 (0.025) | Fatty acid metabolic process |
Vesicular transport | RGP1 | YDR137W | 6.92 (0.031) | Retrograde transport, endosome to Golgi |
| Â | CLC1 | YGR167W | 7.01 (0.049) | Endocytosis |
Mitochondria | RSM24 | YDR175C | 7.01 (0.024) | Mitochondrial translation |
| Â | MRPL27 | YBR282W | 7.00 (0.019) | Mitochondrial translation |
| Â | MRPL16 | YBL038W | 6.97 (0.028) | Mitochondrial translation |
| Â | MRPL37 | YBR268W | 6.98 (0.032) | Mitochondrial translation |
| Â | MRPS5 | YBR251W | 7.00 (0.027) | Mitochondrial translation |
Various | MSS2 | YDL107W | 7.00 (0.035) | Protein insertion |
| Â | ILV1 | YER086W | 6.98 (0.035) | Isoleucine biosynthetic process |
| Â | REF2 | YDR195W | 6.97 (0.072) | mRNA processing |
| Â | CYC8 | YBR112C | 7.00 (0.032) | Chromatin remodeling |
Unknown | AIM44 | YPL158C | 6.97 (0.024) | Biological process unknown |