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Figure 7 | Genome Biology

Figure 7

From: RIDDLE: reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network

Figure 7

RIDDLE performs superiorly in matching disjoint gene subsets. (a-c) RIDDLE matches many disjoint subsets of various gene sets created by dividing KEGG pathway sets (a) and GO biological process sets (b) randomly into non-overlapping halves, and splitting GO biological process sets (c) by those annotated prior to and after 9 February 2007. Note the failure of hypergeometric for all three cases and the incremental improvement obtained by each component and the final combinatory RIDDLE method.

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