Figure 4From: Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant densitiesNormalized coverage distributions. (a) Coverage of genomic subregions, relative to the CCDS, after whole genome SOLiD sequencing. Green, regions specific to REC-set; orange, regions specific to VCR-set; blue, shared regions. 'R/V specific' refers to RefSeq/Vega exons not contained in the CCDS. (b) Proportional difference in relative coverage between capture-sequencing and WGS shows both enrichment (values > 1) and depletion (values < 1) of certain genomic subregions after capture. Green, regions specific to REC-set; orange, regions specific to VCR-set; blue shared regions.Back to article page