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Figure 3 | Genome Biology

Figure 3

From: Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidisand human cells

Figure 3

Changes in extreme modes in S. aureus USA300 with three different concentrations of IQ-143. Red shading indicates lower activities after IQ-143 administration, green shading indicates higher activities, and 'sau' denotes S. aureus. Each row displays six extreme modes (continuously numbered from 1 to 198); numbers given in the fields are the activities for each mode under different concentrations of IQ-143. Also given are the pathways in which the modes are involved. Abbreviations: A, amino acids; E, energy metabolism; F, fatty acids; N, nucleotide metabolism; O, oxidative phosphorylation; T, transporters. All details are also shown in Additional file 1 (Tables S7, S8, and S9; key changes in Tables S18 and S19).

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Genome Biology

ISSN: 1474-760X

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