Hundreds of putatively functional small open reading frames in Drosophila

Table 4 Comparison of smORF searches in different eukaryotic organisms

Organism	smORFs	Percentage of total^a	Experimentally verified^b
Saccharomyces	299	5%	67% (247)
Arabidopsis	941	5%	ND
Mus	1,240	5%	56% (25)
Drosophila	401	3%	ND

Comparison of different smORF searches showing the number of smORFs identified in S. cerevisiae [19], A. thaliana [11], M. musculus [28] and D. melanogatser (this study). ^aThe fraction of smORFs relative to previously annotated protein-coding genes. ^bThe proportion of smORFs with direct experimental evidence of translation and/or function. Numbers in parentheses are the actual numbers of smORFs tested experimentally. ND, not determined.

ISSN: 1474-760X