Table 2 Relating mRNA stability to gene function
From: Genome-wide analysis of mRNA decay patterns during early Drosophiladevelopment
GO term | P-value |
|---|---|
Cellular component | Â |
   Ribosomal subunit | 2.99E-53 |
   Cytosolic ribosome | 6.21E-53 |
   Ribosome | 2.54E-47 |
   Cytosolic part | 6.46E-44 |
   Ribonucleoprotein complex | 5.29E-41 |
   Large ribosomal subunit | 1.75E-33 |
   Cytosolic large ribosomal subunit | 5.77E-33 |
   Small ribosomal subunit | 1.10E-18 |
   Cytosolic small ribosomal subunit | 8.11E-18 |
   Cytosol | 4.65E-16 |
   Nuclear part | 4.04E-10 |
   Organelle lumen | 3.29E-08 |
   Intracellular organelle lumen | 3.29E-08 |
   Mitochondrial ribosome | 4.31E-06 |
   Organellar ribosome | 4.31E-06 |
   Respiratory chain | 1.02E-04 |
   Mitochondrial respiratory chain | 1.02E-04 |
   Mitochondrial membrane part | 1.06E-04 |
   Organelle envelope | 4.06E-04 |
   Envelope | 4.52E-04 |
   Mitochondrial large ribosomal subunit | 6.59E-04 |
   Organellar large ribosomal subunit | 6.59E-04 |
   Mitochondrial membrane | 9.60E-04 |
   Mitochondrial envelope | 3.29E-03 |
   Organelle inner membrane | 3.70E-03 |
   Mitochondrial inner membrane | 5.89E-03 |
   Nuclear lumen | 9.34E-03 |
Gene function | Â |
   Structural constituent of ribosome | 3.24E-49 |
   Structural molecule activity | 5.11E-28 |
   mRNA binding | 6.43E-04 |
   Enzyme binding | 8.66E-04 |
   General RNA polymerase II transcription factor activity | 1.84E-03 |
   Translation regulator activity | 6.07E-03 |
   Translation factor activity, nucleic acid binding | 7.38E-03 |
Biological process | Â |
   Cellular protein metabolic process | 1.74E-32 |
   Mitotic spindle elongation | 9.89E-29 |
   Spindle elongation | 2.47E-28 |
   Gene expression | 2.44E-27 |
   Cellular biopolymer biosynthetic process | 3.35E-23 |
   Cellular macromolecule biosynthetic process | 3.40E-23 |
   Biopolymer biosynthetic process | 3.90E-23 |
   Macromolecule biosynthetic process | 4.56E-23 |
   Translation | 2.21E-19 |
   Protein metabolic process | 3.94E-18 |
   RNA metabolic process | 6.51E-09 |
   Biopolymer modification | 2.33E-08 |
   Protein modification process | 3.57E-08 |
   Phosphorylation | 4.52E-07 |
   Regulation of metabolic process | 5.02E-07 |
   Phosphorus metabolic process | 5.34E-07 |
   Phosphate metabolic process | 5.34E-07 |
   Post-translational protein modification | 1.51E-06 |
   Regulation of macromolecule metabolic process | 2.33E-06 |
   Mitochondrial ATP synthesis coupled electron transport | 6.52E-06 |
   ATP synthesis coupled electron transport | 2.63E-05 |
   Membrane invagination | 3.03E-05 |
   Endocytosis | 3.03E-05 |
   Electron transport chain | 3.67E-05 |
   Regulation of primary metabolic process | 4.98E-05 |
   Oxidative phosphorylation | 5.61E-05 |
   Respiratory electron transport chain | 6.89E-05 |
   RNA processing | 7.50E-05 |
   Regulation of cellular metabolic process | 9.72E-05 |
   Macromolecular complex assembly | 1.33E-04 |
   Macromolecular complex subunit organization | 2.36E-04 |
   Cellular macromolecular complex assembly | 2.42E-04 |
   Membrane organization | 4.64E-04 |
   Cellular macromolecular complex subunit organization | 5.06E-04 |
   Regulation of cellular process | 5.24E-04 |
   Regulation of gene expression | 6.81E-04 |
   Cellular component assembly | 8.16E-04 |
   Cellular respiration | 1.78E-03 |
   Proteolysis involved in cellular protein catabolic process | 2.76E-03 |
   Cellular protein catabolic process | 2.76E-03 |
   Generation of precursor metabolites and energy | 3.36E-03 |
   Energy derivation by oxidation of organic compounds | 3.36E-03 |
   Ribonucleoprotein complex biogenesis | 3.65E-03 |
   Vesicle-mediated transport | 5.40E-03 |
   Regulation of alternative nuclear mRNA splicing, via spliceosome | 7.43E-03 |
   Transcription initiation from RNA polymerase II promoter | 8.09E-03 |
   Cellular biopolymer catabolic process | 9.24E-03 |