Figure 3

Repeats are associated with the nuclear membrane. (a) Coverage of repetitive sequences within LEM-2 subdomains or gaps. Percentages of bases covered by repetitive sequences are plotted. The bottom and top of boxes indicate the 25th and 75th percentiles, respectively, and bands in the boxes indicate medians. Whiskers indicate the lowest or the highest data points within 1.5 × interquartile range from the box. Wilcoxon rank sum test was used for the statistical analysis. (b) Average counts of repetitive sequences across LEM-2 subdomain-gap boundaries. The number of repeats were counted (according to each repeat's central coordinate) within sliding 1 kb windows (500 bp offset) for the 354 boundaries (Materials and methods). The average count in each window is plotted. Average LEM-2 ChIP-chip MA2C scores of sliding windows (100 bp window, 50 bp offsets) are also plotted.