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Table 3 Enriched transcription factor binding sites identified in cluster 1 multi-species conserved elements

From: Motifs and cis-regulatory modules mediating the expression of genes co-expressed in presynaptic neurons

Transcription factor

P-value

FDR (%)

Brief description

AP-2

0.002

0.08

Activating enhancer binding protein 2

ETF

0.006

0.23

TEA domain family member 2

CREB

0.008

0.32

cAMP responsive element binding protein

NRSF

0.008

0.33

RE1-silencing transcription factor

NGFI-C

0.009

0.36

Nerve growth factor/EGR4

MyoD

0.014

0.64

Myogenic differentiation 1

Olf-1

0.016

0.80

Olfactory neuronal TF 1

E2F

0.016

0.80

E2F family in control of cell cycle and tumor suppression

Myogenin

0.028

1.46

Myogenin/nuclear factor 1

NF-kappaB

0.028

1.46

Nuclear factor of kappa light polypeptide gene

c-Myc:Max

0.030

1.57

Myc proto-oncogene

Sp1

0.034

1.82

Trans-acting specific protein 1

AP-4

0.038

2.07

Activating enhancer binding protein 4

Nrf-1

0.039

2.08

Nuclear respiratory factor 1

HNF4

0.041

2.21

Hepatocyte nuclear factor 4

LXR

0.047

2.60

Liver × receptor

  1. The enrichment of 16 transcription factor binding sites over-represented in MCEs from cluster 1 genes in comparison to those in cluster 2 or 3 genes with a P-value < 0.05. FDR, false discovery rate.
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Genome Biology

ISSN: 1474-760X

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