Table 3 Estimation of tumor content by segmentation in the CRL-2324 dilution series (data set 3)

From: Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays

	Hemizygous loss 18q21.32-q22.3^†			Single copy gain 13q11-q12.3^‡			CNN LOH 13q21.31-qter^§
Tumor (%)*	Expected mBAF	Observed mBAF	Tumor (%)	Expected mBAF	Observed mBAF	Tumor (%)	Expected mBAF	Observed mBAF	Tumor (%)
0	0.5	0.53	12	0.5	0.53	15	0.5	0.53	6
10 (7-12)	0.53	0.53	11	0.52	0.53	12	0.55	0.54	7
14 (10-17)	0.54	0.53	12	0.53	0.53	12	0.57	0.55	9
21 (17-26)	0.56	0.55	18	0.55	0.54	16	0.6	0.58	16
23 (18-28)	0.56	0.6	32	0.55	0.56	28	0.62	0.64	28
30 (24-35)	0.59	0.58	27	0.57	0.55	21	0.65	0.62	24
34 (28-40)	0.60	0.59	31	0.57	0.55	23	0.67	0.64	29
45 (38-51)	0.65	0.61	37	0.59	0.56	27	0.72	0.67	33
47 (40-54)	0.65	0.65	46	0.6	0.57	35	0.74	0.71	42
50 (43-57)	0.67	0.64	43	0.6	0.57	30	0.75	0.7	39
79 (74-83)	0.83	0.84	81	0.64	0.6	51	0.9	0.89	77
100	1	0.93	93	0.67	0.65	88	1	0.95	89

*95% confidence interval within parentheses. ^†Hemizygous loss chr18:54400001-71300000. ^‡Single copy gain chr13:16000001-31100000. ^§Copy number neutral LOH chr13:60500001-114142980.

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