Modeling synthetic lethality

Table 1 Multi-protein complexes with a significant number of 'within' synthetic genetic interactions (Bonferroni adjusted P-value < 0.001)

Complex	Odds	Expected	Size	Interact	Tested	Essential	Name
GO:0000778	161.91	0.24	33	18	33	19	Condensed nuclear chromosome k
GO:0000776	73.38	0.13	20	6	17	7	Kinetochore

Multi-protein complexes with a significant number of 'within' synthetic genetic interactions (adjusted P-value < 0.001). Odds, odds ratios; Expected, expected number of synthetic genetic interactions per multi-protein complex; Size, number of genes in the multi-protein complex; Interact, number of observed interactions (positive edges); Tested, number of interactions (edges) tested; Essential, total number of essential genes in the multi-protein complex; Name, full name.

ISSN: 1474-760X