Figure 8

Cancer core program genes before and after cell cycle subtraction. Genes overexpressed in >20/32 data sets and with an average DT rank <1,000 are marked in red and their names are listed below the table (left panel). Analogously for the right panel, with the parameter relaxed to overexpression in >15/32 data sets to account for the reduced number of genes after elimination of CC genes. Genes belonging to the GO category 'cell cycle' are marked as orange asterisks (and with orange boxes in the right panel) to allow a better assessment of the effects of CC subtraction.