Gene name | Symbol | Acc. Number | Array cell | Fold change | SD | Cell cycle function |
---|---|---|---|---|---|---|
V-abl Abelson murine leukemia viral oncogene homolog 1 | ABL1 | NM_005157 | A01 | 18.25 | 3.19 | S phase and DNA replication and regulation |
Cullin 2 | CUL2 | NM_003591 | D10 | 14.32 | 1.89 | G1 phase and G1/S transition and checkpoint and arrest |
B-cell CLL/lymphoma 2 | BCL2 | NM_000633 | A09 | 12.44 | 2.12 | Regulation |
Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | CDKN2B | NM_004936 | D03 | 11.03 | 2.37 | Checkpoint and arrest and negative regulator |
Anaphase promoting complex subunit 4 | ANAPC4 | NM_013367 | A03 | 9.17 | 0.27 | G2 phase and G2/M transition and regulation |
Cullin 3 | CUL3 | NM_003590 | D11 | 8.46 | 0.65 | G1 phase and G1/S transition and checkpoint and arrest |
Cyclin-dependent kinase 5, regulatory subunit 1 (p35) | CDK5R1 | NM_003885 | C07 | 8.00 | 1.66 | Regulation |
RAD1 homolog | RAD1 | NM_002853 | F09 | 7.43 | 0.48 | Checkpoint and arrest |
SERTA domain containing 1 | SERTAD1 | NM_013376 | G06 | 7.41 | 0.27 | G2 phase and G2/M transition |
Ataxia telangiectasia and Rad3 related | ATR | NM_001184 | A06 | 6.51 | 0.36 | Checkpoint and arrest |
Ubiquitin-activating enzyme E1 | UBE1 | NM_003334 | G12 | 6.48 | 1.19 | S phase and DNA replication |
Dynamin 2 | DNM2 | NM_004945 | E01 | 5.38 | 0.37 | G2 phase and G2/M transition |
Cell division cycle 16 homolog | CDC16 | NM_003903 | C01 | 4.94 | 0.43 | M phase |
HUS1 checkpoint homolog | HUS1 | NM_004507 | E07 | 4.89 | 0.74 | Checkpoint and arrest |
Cyclin-dependent kinase 8 | CDK8 | NM_001260 | C11 | 4.86 | 1.25 | Regulation |
RAD51 homolog (RecA homolog) | RAD51 | NM_002875 | F11 | 4.77 | 3.09 | M phase |
Menage a trois homolog 1, cyclin H assembly factor | MNAT1 | NM_002431 | F05 | 4.51 | 0.18 | G2 phase and G2/M transition |
Tumor protein p53 (Li-Fraumeni syndrome) | TP53 | NM_000546 | G11 | 4.40 | 1.48 | Checkpoint and arrest |
Cyclin-dependent kinase 2 | CDK2 | NM_001798 | C05 | 4.07 | 0.24 | Checkpoint and arrest and regulation |
Anaphase promoting complex subunit 2 | ANAPC2 | NM_013366 | A02 | 3.76 | 0.63 | G1 phase and G1/S transition and regulation |
Growth arrest and DNA-damage-inducible, alpha | GADD45A | NM_001924 | E03 | 3.70 | 0.08 | Checkpoint and arrest and regulation |
Cyclin-dependent kinase inhibitor 1B (p27, Kip1) | CDKN1B | NM_004064 | D01 | 3.65 | 0.25 | G1 phase and G1/S transition and checkpoint and arrest |
Cyclin-dependent kinase inhibitor 3 | CDKN3 | NM_005192 | D04 | 3.36 | 0.09 | G1+G2 phase and G1/S + G2/M transition and checkpoint and arrest |
CDK5 regulatory subunit associated protein 1 | CDK5RAP1 | NM_016408 | C08 | 3.32 | 0.06 | G2 phase and G2/M transition |
Cyclin F | CCNF | NM_001761 | B07 | 3.22 | 0.20 | M phase and regulation |
Cyclin-dependent kinase 6 | CDK6 | NM_001259 | C09 | 3.22 | 0.23 | G1 phase and G1/S transition and regulation |
DIRAS family, GTP-binding RAS-like 3 | DIRAS3 | NM_004675 | A04 | 3.15 | 0.12 | ? |
CHK1 checkpoint homolog | CHEK1 | NM_001274 | D05 | 2.95 | 0.15 | Checkpoint and arrest |
Nibrin | NBN | NM_002485 | F07 | 2.89 | 0.03 | Checkpoint and arrest |
Retinoblastoma-like 2 (p130) | RBL2 | NM_005611 | G04 | 2.89 | 0.83 | Negative regulator |
Cell division cycle 34 homolog | CDC34 | NM_004359 | C04 | 2.86 | 0.14 | G1 phase and G1/S transition and checkpoint and arrest |
Cyclin G2 | CCNG2 | NM_004354 | B09 | 2.81 | 0.18 | Checkpoint and arrest |
BCL2-associated X protein | BAX | NM_004324 | A07 | 2.76 | 0.06 | Negative regulator |
Proliferating cell nuclear antigen | PCNA | NM_182649 | F08 | 2.76 | 0.19 | S phase and DNA replication |
SMT3 suppressor of mif two 3 homolog 1 | SUMO1 | NM_003352 | G08 | 2.73 | 0.10 | S phase and DNA replication |
Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | CDKN1A | NM_000389 | C12 | 2.67 | 0.08 | Checkpoint and arrest and regulation |
Hect domain and RLD 5 | HERC5 | NM_016323 | E06 | 2.54 | 0.04 | G2 phase and G2/M transition |
Cyclin-dependent kinase 4 | CDK4 | NM_000075 | C06 | 2.52 | 0.13 | G1 phase and G1/S transition and regulation |
G-2 and S-phase expressed 1 | GTSE1 | NM_016426 | E05 | 2.49 | 0.10 | G2 phase and G2/M transition |
Cyclin T2 | CCNT2 | NM_001241 | B12 | 2.41 | 0.16 | G2 phase and G2/M transition and regulation |
Breast cancer 2, early onset | BRCA2 | NM_000059 | A12 | 2.36 | 0.27 | Checkpoint and arrest and regulation |
Retinoblastoma-like 1 (p107) | RBL1 | NM_002895 | G03 | 2.31 | 0.04 | Negative regulator |
MCM5 minichromosome maintenance deficient 5 | MCM5 | NM_006739 | F03 | 2.28 | 0.13 | S phase and DNA replication |
CDC28 protein kinase regulatory subunit 1B | CKS1B | NM_001826 | D07 | 2.28 | 0.03 | G2 phase and G2/M transition and regulation |
Cell division cycle 20 homolog | CDC20 | NM_001255 | C03 | 2.24 | 0.17 | Regulation |
Cyclin C | CCNC | NM_005190 | B03 | 2.16 | 0.14 | Regulation |
MAD2 mitotic arrest deficient-like 2 | MAD2L2 | NM_006341 | E11 | 2.03 | 0.46 | Checkpoint and arrest |
Transcription factor Dp-1 | TFDP1 | NM_007111 | G09 | -22.50 | 1.04 | Regulation |