Skip to main content

Table 2 Pfam families with the highest and lowest SNP A/S ratios

From: Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective

Pfam accession

A/S ratio

Number of proteins

Pfam description

PF05296

0.49

55

Mammalian taste receptor protein (TAS2R)

PF00001

0.49

558

7 transmembrane receptor (rhodopsin family)

PF02798

0.47

20

Glutathione S-transferase, amino-terminal domain

PF00043

0.46

24

Glutathione S-transferase, carboxy-terminal domain

PF01454

0.45

24

MAGE family

PF09723

0.44

42

Putative regulatory protein (CxxC_CxxC_SSSS)

PF02023

0.44

39

SCAN domain

PF00059

0.43

58

Lectin C-type domain

PF07859

0.42

21

alpha/beta Hydrolase fold

PF00048

0.40

23

Small cytokines (intecrine/chemokine), interleukin-8 like

PF00105

0.14

38

Zinc finger, C4 type (two domains)

PF00536

0.14

68

SAM domain (Sterile alpha motif)

PF07649

0.13

45

C1-like domain

PF00125

0.13

25

Core histone H2A/H2B/H3/H4

PF00535

0.13

27

Glycosyl transferase family 2

PF01437

0.13

31

Plexin repeat

PF00335

0.13

23

Tetraspanin family

PF00350

0.12

28

Dynamin family

PF07707

0.11

36

BTB And C-terminal Kelch

PF00433

0.09

33

Protein kinase C terminal domain

  1. Top part: ten families with the highest A/S ratios. Bottom part: ten families with the lowest A/S ratios.