Figure 2

A TGFβ signature detects TGFβ pathway activation following short-term Ras induction in the mammary gland. (a) Mapping of mammary glands expressing activated Ras for increasing times (filled triangles) or uninduced controls (open triangles) onto the principal component space defined by the TGFβ signature in Figure 1a. (b) SVD regression predicts TGFβ pathway activation in mammary glands expressing activated Ras for 96 h, 8 days, and 14 days.