Rapid identification of PAX2/5/8 direct downstream targets in the otic vesicle by combinatorial use of bioinformatics tools

Table 2 Candidate genes selected for experimental validation

Gene	Human EnsEMBL ID	GXD	ZFIN	TM	Matrix
Clones specifically expressed in otic vesicle and Pax2 responsive
Mtrnl	ENSG00000176845		√		B
ccdc102a	ENSG00000135736		√		B
sec31l	ENSG00000138674		√		A
cldn7	ENSG00000181885		√		A
brn2	ENSG00000184486	√			A
Clones specifically expressed in otic vesicle
iba1	ENSG00000126878	√	√		B
erlectin	ENSG00000068912		√		A
cldn4	ENSG00000189143		√		B
Bmcp1	ENSG00000102078			√	A
Clones ubiquitously expressed
lamp1	ENSG00000185896			√	A
Clones not expressed in otic vesicle
bhlhb5	ENSG00000180828	√			B
mvp	ENSG00000013364		√	√	A
slim1	ENSG00000022267			√	B
eps15l1	ENSG00000127527	√			A

ISSN: 1474-760X