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Table 9 Expression of APC, DC and myeloid signature genes in CD16 cells

From: Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

  

Dendritic cells

Myeloid cells

 

Ratio to DC

Probe set ID

Gene

BDCA1

BDCA3

pDC

Mono

Neu

CD16 cells

CD16

Mono

Neu

APC signature genes

          

203932_at

HLA-DMB

8,636*

7,929

5,894

5,194

173

2,581

0.3

0.6

<0.1

205101_at

CIITA

2,803

2,354

724

531

50

226

<0.1

0.2

<0.1

219574_at

MARCH1

587

777

544

1,214

58

810

1

2

<0.1

201425_at

ALDH2

9,279

7,841

6,034

8,504

706

1,760

0.2

0.9

<0.1

222891_s_at

BCL11A

569

747

4,502

310

50

213

<0.1

<0.1

<0.1

205504_at

BTK

1,120

822

1,132

1,409

281

1,786

2

1

0.3

202295_s_at

CTSH

6,197

2,528

1,211

3,949

75

2,440

0.39

0.6

<0.1

213831_at

DQA1

11,535

7,503

5,919

4,701

50

252

<0.1

0.4

<0.1

215536_at

DQB2

432

391

157

180

81

52

0.1

0.4

0.2

209312_x_at

DRB1

14,608

14,477

13,250

11,915

228

14,007

1

0.8

<0.1

209619_at

CD74

12,533

12,210

10,498

9,020

867

7,383

0.6

0.7

<0.1

210042_s_at

CTSZ

906

848

692

370

153

673

0.7

0.4

0.2

201560_at

CLIC4

920

305

663

3,023

165

354

0.4

3

0.2

217388_s_at

KYNU

2,414

1,059

2,204

3,516

50

3,738

2

1

<0.1

203927_at

NFKBIE

529

272

232

197

63

290

0.5

0.4

0.1

220998_s_at

UNC93B1

966

850

1,938

862

449

1,235

0.6

0.4

0.2

Pan-DC signature genes

          

206674_at

FLT3

3,032

5,883

2,169

208

<50

<50

<0.1

<0.1

<0.1

219256_s_at

SH3TC1

1,263

899

1,128

392

166

858

0.7

0.3

0.1

218617_at

TRIT1

1,159

1,246

1,851

509

<50

339

0.2

0.3

<0.1

231810_at

BRI3BP

691

735

836

298

146

279

0.3

0.4

0.2

209139_s_at

PRKRA

846

1,067

1,440

316

74

497

0.3

0.2

<0.1

225764_at

ETV6

2,172

2,432

1,726

1,143

938

941

0.4

0.5

0.4

208837_at

TMED3

1,317

1,852

1,859

665

<50

1,022

0.6

0.4

<0.1

219218_at

BAHCC1

87

86

250

<50

<50

<50

0.2

0.2

0.2

1552256_a_at

SCARB1

325

425

942

165

128

59

<0.1

0.2

0.1

Non-DC signature genes

          

219243_at

GIMAP4

68

<50

<50

4,404

3,504

1,334

20

65

52

221704_s_at

VPS37B

54

<50

<50

593

962

487

9

11

18

204891_s_at

LCK

<50

<50

<50

92

181

65

-

-

-

214582_at

PDE3B

78

<50

<50

129

625

114

1

2

8

Myeloid signature genes

          

225987_at

STEAP4

<50

<50

<50

877

6,090

<50

-

-

-

1552773_at

CLEC4D

<50

<50

<50

452

520

<50

-

-

-

222934_s_at

CLEC4E

214

124

133

2,837

5,885

229

1

13

28

202974_at

MPP1

591

281

377

3,721

2,408

1,341

2

6

4

205098_at

CCR1

93

<50

115

3,712

3,627

106

1

32

31

223044_at

SLC40A1

769

276

321

5,018

3,444

<50

-

6

4

224341_x_at

TLR4

94

<50

<50

1,411

2,869

540

6

15

31

204714_s_at

F5

<50

<50

<50

1,392

2,313

<50

-

-

-

203561_at

FCGR2A

1,010

44

51

2,985

7,151

2,857

3

3

7

210772_at

FPRL1

<50

<50

<50

389

3,454

70

3

-

-

204924_at

TLR2

904

211

57

2,870

5,548

1,606

2

3

6

215223_s_at

SOD2

1,474

946

528

3,528

7,599

4,236

3

2

5

222218_s_at

PILRA

1,168

150

136

2,899

4,035

3,982

3

2

3

210423_s_at

SLC11A1

81

60

38

1,767

2,930

3,334

41

22

36

203045_at

NINJ1

357

66

71

1,104

3,129

1,934

5

3

9

201669_s_at

MARCKS

521

389

<50

2,449

3,224

1,730

3

5

6

207697_x_at

LILRB2

1,271

78

774

3,353

3,711

4,903

4

3

3

1553297_a_at

CSF3R

1,902

409

156

3,433

6,687

282

0.2

2

4

220088_at

C5AR1

56

34

93

2,316

5,099

3,824

41

25

55

221698_s_at

CLEC7A

3,229

4,295

79

6,642

7,061

5,680

1

2

2

204204_at

SLC31A2

442

187

<50

1,579

2,047

1,671

4

4

5

  1. *Average expression across replicates. Mono, monocyte; neu, neutrophil.