Table 1 Comparative analysis of enhancer trap screens
From: Transposons as tools for enhancer trap screens in vertebrates
Model animal | Vector | Reporter | Promoter | Insertion bias | Insertion ite | Remobilization of vector | Footprint | Mutation | Tissue-specific pattern | Number of lines | Ref. |
|---|---|---|---|---|---|---|---|---|---|---|---|
Medaka fish (Oryzeas latipes) | SB10 | GFP | cska (ubiquitous) | NA | TA | Possible | NA | NA | + | 174 | [17] |
Zebrafish (Danio rerio) | Tol2 | GFP | Mini-keratin8 (tissue specific) | ≥ 50% close to/inside genes | Variable | Possible, shown | Variable | Possible | + | 37 | [10,35] |
Zebrafish | SB10 | GFP | ef1α (ubiquitous) | ≥ 50% close to/inside genes | TA | Possible, shown | NA | Possible | + | 9 | [13] |
Zebrafish | MLV provirus | YFP | gata2 (tissue specific) | Close to/inside genes | Variable | Not possible | NA | About 5% to 10% of insertions | + | 95 | [22] |