Table 6 Functional annotations (GO, KEGG, Biocarta) enriched in transcripts downregulated* in BMP2+ cells compared to control cells in seven-day-old EBs and to undifferentiated BMP2 ES cells
Category | Term | Count | p value |
|---|---|---|---|
GOTERM_BP_5 | DNA metabolism | 15 | 8.4E-5 |
GOTERM_BP_5 | M phase of mitotic cell cycle | 7 | 5.2E-4 |
GOTERM_BP_5 | Carboxylic acid metabolism | 11 | 2.8E-3 |
GOTERM_CC_5 | Chromosome | 9 | 3.8E-3 |
GOTERM_BP_5 | Biopolymer modification | 22 | 9.4E-3 |
GOTERM_MF_5 | Pyrophosphatase activity | 10 | 9.5E-3 |
GOTERM_BP_5 | Amino acid metabolism | 6 | 3.2E-2 |
GOTERM_BP_5 | Recombinational repair | 2 | 3.9E-2 |
GOTERM_BP_5 | Cellular protein metabolism | 31 | 4.2E-2 |
GOTERM_CC_5 | Heterotrimeric G-protein complex | 3 | 4.3E-2 |
GOTERM_MF_5 | Metalloendopeptidase activity | 4 | 5.0E-2 |
GOTERM_CC_5 | Chromosome, periventric region | 3 | 5.9E-2 |
GOTERM_CC_5 | Condensed chromosome | 3 | 6.4E-2 |
GOTERM_BP_5 | Lipid biosynthesis | 5 | 7.5E-2 |
KEGG_PATHWAY | Pyruvate metabolism | 3 | 7.7E-2 |
GOTERM_BP_5 | Steroid biosynthesis | 3 | 8.3E-2 |
GOTERM_BP_5 | Double-strand break repair | 2 | 8.4E-2 |
GOTERM_BP_5 | Regulation of smooth muscle contraction | 2 | 8.4E-2 |
GOTERM_MF_5 | Phosphoric hydrolase activity | 3 | 9.4E-2 |
GOTERM_MF_5 | AMP binding | 2 | 9.7E-2 |