From: Meta-analysis of primary target genes of peroxisome proliferator-activated receptors
Genomic region | Predicted binding | Response in RGA | Association of PPARα | Association of RXRα | Association of pPol II | PPRE status |
---|---|---|---|---|---|---|
ACOX1 intron 1 | Strong | + | + | + | + | + |
APOC3 proximal | Weak | Down | + | + | + | + |
APOC3 published | Medium | Down | + | + | - | + |
APOA1 proximal | Weak | +/down | + | + | + | + |
CPT1B | Strong | + | - | - | - | ± |
PPARα proximal | Medium | + | + | + | + | + |
RVRα proximal | Medium | + | + | + | + | + |
RVRα TSS | No DR1 | - | +* | +* | +* | - |
UCP3 proximal | Medium | Down | + | + | + | Â |
ACOX1 distal | Medium | - | - | - | - | - |
ACOX1 published | Not binding | - | - | - | - | - |
ANGPLT4 distal | Weak | +/down | + | + | - | + |
APOC3 distal 1 | Medium | ± | - | - | - | - |
APOC3 distal 2 | Medium | ± | - | - | - | - |
PPARα distal | Strong | +/down | + | + | + | + |
RVRα distal | Weak | - | + | + | - | ± |
SULT2A1 | Strong | + | + | + | + | + |
UCP3 distal | Strong | + | + | + | + | + |
ACOX1 intron 2 | Medium | + | + | + | + | + |
ANGPTL4 cluster | Strong | + | - | + | + | + |
APOC3 intron | Strong | + | - | - | - | ± |
UCP3 cluster | Weak | - | - | - | - | - |
UCP3 intron | Medium | Down | + | + | + | + |