From: Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans
Biologic process/molecular functiona | mRNA levels in aging versus young adult glp-1s | Proportion changedb | P valueb |
---|---|---|---|
Larval development | Decreased | 112/842 | <0.0001 |
Ion transport | Decreased | 113/504 | <0.0001 |
Generation of precursor metabolites and energy | Decreased | 78/474 | <0.0001 |
Structural constituents of cuticle | Decreased | 88/144 | <0.0001 |
Lipid metabolism | Decreased | 24/145 | <0.0001 |
Oxidative phosphorylation | Decreased | 13/44 | <0.0001 |
Aging (C elegans) | Decreased | 12/58 | 0.003 |
Catalytic activity | Decreased | 215/2734 | 0.0004 |
Glycolysis | Decreased | 4/15 | 0.014 |
Positive regulation of growth | Increased | 124/928 | <0.0001 |
Cytoskeleton | Increased | 21/108 | 0.0003 |
Rab-related GTPase protein-mediated vesicular trafficking | Increased | 16/72 | 0.0003 |
Aging (C elegans) | Increased | 10/58 | 0.004 |
Osmoregulation | Increased | 21/137 | 0.007 |
Locomotion | Increased | 24/144 | 0.001 |