From: Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans
 |  | Measuredb expression | Percentage repair after 24 hours | ||
---|---|---|---|---|---|
Genomic target | Estimateda transcription in adults | young adult glp-1s | aging adult glp-1s | young adult glp-1s | aging adult glp-1s |
Low transcription genes | |||||
   par-2 (ubiquitin ligase; F58B6.3b) | None/low | 10a | 12a | 61 ± 2 | 33 ± 10 |
   pax-3 (homeodomain transcription factor; F27E5.2) | Low | 2a | 3a | 49 ± 1 | 25 ± 4 |
   lin-39 (HOX domain transcription factor; C07H6.7) | None/low | 22a | 48a | 55 ± 1 | 30 ± 2 |
   nob-1 (HOX domain transcription factor; Y75B8A.2) | None/low | 12a | 13a | 60 ± 3 | 22 ± 2 |
   Average |  |  |  | 56 ± 3 | 28 ± 2 |
Medium transcription genes | |||||
   unc-2 (calcium channel α subunit; T02C5.5a) | Medium | 19 | 42 | 55 ± 1 | 29 ± 8 |
   polymerase epsilon (F33H2.5), F33H2.6, and part of dog-1 | Medium | 54 | 288 | 63 ± 5 | 32 ± 4 |
   atl-1 (ATM-like protein kinase; T06E4.3) | Medium | 88 | 146 | 70 ± 1 | 32 ± 1 |
   Average |  |  |  | 63 ± 4 | 31 ± 2 |
High transcription genes | |||||
   act-1, act-2, act-3 (T04C12.6, T04C12.5, T04C12.4), and about 3 kb noncoding | High | 7,541 | 6,881 | 66 ± 2 | 39 ± 5 |
   unc-44 (ankyrin; B0350.2a.1) | High | 501 | 765 | 66 ± 4 | 48 ± 5 |
   act-4 (M03F4.2), M03F4.6, and M03F4.7 | High | 4,018 | 3,946 | 63 ± 5 | 41 ± 3 |
   Average |  |  |  | 65 ± 1 | 42 ± 3 |