Skip to main content

Table 6 Results from high-fat diet experiment

From: Statistical tools for synthesizing lists of differentially expressed features in related experiments

 

Joint Bayesian model

Hwang et al.'s method

Rules

q

R(q)

O 11

O 1+

O +1

CI 95

DE

nonDE

Max

0.02

3.83

49

1,893

85

2.72-4.68

3,746

8,742

Double

0.07

2.04

226

3,059

452

1.90-2.21

3,746

8,742

  1. The joint model returns R(q max ) = 3.83 with an associated credibility interval [3.17-4.44]. The conditional model shows the same results (data not reported). The R(q2) is 2.04 and the CI is 1.90-2.21. The procedure indicates clearly a significant association between the two lists. Hwang et al.'s method calls 3,746 genes as differentially expressed (DE). All the genes called by our method are included in their list.