Figure 3

Expression conservation between duplicates and their ancestors. (a) Each dot represents the EC of a duplicate pair where the EC of the less conserved duplicate is shown on the x-axis and the EC of the more conserved duplicate is shown on the y-axis. The yellow region indicates similar rates of expression divergence (y - x < 0.2) and the green region indicates asymmetric rates of expression divergence (y - x > 0.5). The dashed line indicates a threshold of EC > 0.37, which is the 0.05 significance value from randomly selected S. cerevisiae-C. albicans gene pairs (see Figure 2b). (b) Distribution of EC for the least conserved duplicates among the 96 cases where the more conserved duplicate has significantly high EC (above the dashed line in (b)). (c) EC between the least conserved duplicate and the reconstructed ancestral expression (x-axis), and between the C. albicans ortholog and the reconstructed ancestral expression (y-axis). Red dots correspond to duplicates with asymmetric expression divergence (left peak in (b)) and blue dots correspond to duplicates with conserved expression (both copies with EC > 0.37).