On the association between chromosomal rearrangements and genic evolution in humans and chimpanzees

Table 3 Comparison of genes overlapping segmental duplications

	Genes overlapping shared SDs			Genes overlapping human specific SDs			Genes overlapping chimp specific SDs
	Genes outside SDs	Genes within SDs	P value	Genes outside SDs	Genes within SDs	P value	Genes outside SDs	Genes within SDs	P value
N	5,804	330		5,804	720		5,804	1,364
K_I	0.0121	0.0121	0.574	0.0121	0.0122	0.032	0.0121	0.0121	0.127
K_A	0.0029	0.0030	0.502	0.0029	0.0040	< 0.001	0.0029	0.0025	0.001
K_S	0.0127	0.0110	0.009	0.0127	0.0138	0.016	0.0127	0.0118	0.005
K_A/K_I	0.2360	0.2425	0.713	0.2360	0.3126	< 0.001	0.2360	0.2068	0.002

Genes in sex chromosomes, in telomeres, centromeres and chromosome 19 were removed before this analysis to avoid known confounding factors.

ISSN: 1474-760X