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Table 2 Performance of the CNVfinder algorithm using validated data after wave correction

From: Breaking the waves: improved detection of copy number variation from microarray-based comparative genomic hybridization

  

Calls

Status

Number of regions

A

B

C

D

E

Unvalidated

25

4

3

4

3

2

Validated

112

71

70

75

57

36

Total

137

75

73

79

60

38

False discovery rate

 

5

4

5

5

5

Sensitivity (confidence interval)

 

63 (54, 72)

62 (53, 72)

67 (57, 76)

51 (41, 61)

32 (24, 42)

Specificity (confidence interval)

 

84 (66, 95)

88 (71, 97)

84 (66, 95)

88 (71, 97)

92 (77, 99)

  1. The number of regions called in five replicate experiments (A to E, ranked by standard deviation) using CNVfinder after wave correction. The false discovery rate, sensitivity and specificity are quoted as percentages and the confidence intervals quoted are the 95% intervals.