Figure 3

SLC1A3 and related genes. Four large-scale gene expression databases are used in this study. The arrows point to the genes found using the liquid association score system, according to the search method described in Figure 2b. The color of a line/arrow shows which database is used in the analysis. P values are calculated by randomization test. For descriptions of gene symbols, see Table 2. All four major multiple sclerosis loci for the Finnish scan have representative genes in this chart: MBP from 18q23, PRKCA from 17q22-q23.2, SLC1A3 from 5p13, and the HLA locus at 6p21.3. Also shown are two separate lists of genes correlated with MBP and with SLC1A3 most strongly. CTNND2 (located at 5p15.2) is seen in both lists.