Figure 5

Positional gene enrichment analysis of genes on chromosome 17. Positional gene enrichment analysis for the genes that are more highly expressed in neuroblastoma compared to normal neuroblasts identified two regions on 17q with significant over-representation (-¹⁰log P values; indicated in grey; the genes in these regions are printed in the boxes). The horizontal red line indicates the multiple testing corrected P value of 0.01, above which the positional gene enrichment value denotes significant over-representation. Vertical lines show the position of the genes on chromosome 17 from the gene list under investigation. The boxplot shows the gene density along the chromosome.