Organism (abbreviation) | Protein name* | Accession number†| Gene ID | Chromosome | PDB ID‡ | Function§ |
---|---|---|---|---|---|---|
Insects | Â | Â | Â | Â | Â | Â |
Anopheles gambiae, mosquito (Ag) | PGRP-LA | XM_314105 | 1274911 | 2L | - | - |
 | PGRP-LB | XM_321943 | 1281956 | 2R | - | Predicted amidase |
 | PGRP-LC1 | XM_314103 | 1274909 | 2L | - | - |
 | PGRP-LC2 | XM_558599 | 1274909 | 2L | - | - |
 | PGRP-LC3 | XM_558600 | 1274909 | 2L | - | - |
 | PGRP-S1 | XM_310547 | 1271702 | X | - | - |
 | PGRP-S2 | XM_557000 | 3290146 | 2L | - | - |
 | PGRP-S3 | XM_316359 | 1276947 | 2L | - | Predicted amidase |
 | PGRP-SC2 | XM_316360 | 1276948 | 2L | - | Predicted amidase |
Apis mellifera, honey bee (Am) | PGRP-L | XM_392452 | 408924 | LG7 | - | - |
 | PGRP-S | XM_395941 | 412484 | LG13 | - | Predicted amidase |
Bombyx mori, domestic silkworm (Bm) | BTL-LP1 | AB017519 | - | - | - | Predicted amidase |
 | BTL-LP2 | AB017520 | - | - | - | - |
 | PGRP | AF441723 | - | - | - | - |
 | PGRP-S | AB016249 | - | - | - | PPO activation [36] |
Calpodes ethlius, Brazilian skipper butterfly (Ce) | PGRP-S | AF035445 | - | - | - | - |
Drosophila melanogaster, fruit fly (Dm) | PGRP-LA-C | NM_206306 | 39062 | 3L 67A7 | - | - |
 | PGRP-LA-D(a) | NM_206305 | 39062 | 3L 67A7 | - | - |
 | PGRP-LA-E | NM_206304 | 39062 | 3L 67A7 | - | - |
 | PGRP-LA-F(b) | NM_206307 | 39062 | 3L 67A7 | - | - |
 | PGRP-LB-A | NM_141822 | 41379 | 3R 86E8 | 1OHT | Amidase [7,40] |
 | PGRP-LB-B | NM_169393 | 41379 | 3R 86E8 | - | Predicted amidase |
 | PGRP-LB-C | NM_169392 | 41379 | 3R 86E8 | - | Predicted amidase |
 | PGRP-LC-A(x) | NM_168324 | 39063 | 3L 67A8 | 2F2L | Imd activation [19,25,29-34], phagocytosis [31] |
 | PGRP-LC-B(a) | NM_140041 | 39063 | 3L 67A8 | 1Z6I, 2F2L | Imd activation [19,29-34] |
 | PGRP-LC-C(y) | NM_206308 | 39063 | 3L 67A8 | - | Imd activation [33] |
 | PGRP-LD-A | NM_001031942 | 3771920 | 3L 67A8 | - | - |
 | PGRP-LE | NM_132850 | 32534 | X 13F1 | 2CB3 | Imd and PPO activation [35] |
 | PGRP-LF | NM_140042 | 39064 | 3L 67A8-67A9 | - | - |
 | PGRP-SA | NM_132499 | 32099 | X 10C6 | 1SXR, 1S2J | Toll activation [8], carboxypeptidase [12], phagocytosis [24] |
 | PGRP-SB1 | NM_140660 | 39870 | 3L 73C1 | - | Predicted amidase |
 | PGRP-SB2 | NM_140659 | 39869 | 3L 73C1 | - | Predicted amidase |
 | PGRP-SC1a¶ | NM_136563 | 35859 | 2R 44E2 | - | Amidase [14], Toll activation [24], phagocytosis [24] |
 | PGRP-SC1b¶ | NM_136565 | 35861 | 2R 44E2 | - | Amidase [14] |
 | PGRP-SC2 | AJ55662 | - | 2R 44E2 | - | Predicted amidase |
 | PGRP-SD | AJ556628 | - | 3L 66A8 | - | Toll activation [23] |
Glossina morsitans, tsetse fly (Glm) | PGRP-LB | DQ307160 | - | - | - | Predicted amidase |
 | PGRP-LC | DQ307161 | - | - | - | - |
Galleria mellonella, greater wax moth (Gm) | PGRP-A | AF394583 | - | - | - | - |
 | PGRP-B | AF394587 | - | - | - | - |
Holotrichia diomphalia, beetle (Hd) | PGRP-1 | AB115774 | - | - | - | PPO activation [38] |
 | PGRP-2 | AB115775 | - | - | - | - |
 | PGRP-3 | AB115776 | - | - | - | - |
Manduca sexta, tobacco hornworm (Ms) | PGRP-1A | AF413068 | - | - | - | - |
 | PGRP-1B | AF413061 | - | - | - | - |
Tenebrio molitor, yellow mealworm (Tm) | PGRP-SA | AB219970 | - | - | - | PPO activation [37] |
Trichoplusia ni, cabbage looper (Tn) | PGRP-S | AF076481 | - | - | - | - |
Mollusks | Â | Â | Â | Â | Â | Â |
Argopecten irradians, bay scallop (Ai) | PGRP | AY437875 | - | - | - | Predicted amidase |
Euprymna scolopes, Hawaiian bobtail squid (Es) | PGRP-1 | AY956811 | - | - | - | Predicted amidase |
 | PGRP-2 | AY956812 | - | - | - | Predicted amidase |
 | PGRP-3 | AY956813 | - | - | - | Predicted amidase |
 | PGRP-4 | AY956814 | - | - | - | - |
Echinoderms | Â | Â | Â | Â | Â | Â |
Asterias rubens, European starfish (Ar) | PGRP-S1a | DQ222477 | - | - | - | Predicted amidase |
 | PGRP-S2a | DQ222478 | - | - | - | Predicted amidase |
Strongylocentrotus purpuratus, purple sea urchin (Sp) | PGRP-S | XM_781925 | 581948 | - | - | Predicted amidase |
Fish | Â | Â | Â | Â | Â | Â |
Danio rerio, zebrafish (Dr) | PGLYRP-2 | DQ447202 | 568634 | 8 | - | Predicted amidase |
 | PGLYRP-5 | DQ447203 | 553387 | 18 | - | Predicted amidase |
 | PGLYRP-6 | DQ447204 | 571817 | - | - | Predicted amidase |
Tetraodon nigroviridis, spotted green pufferfish (Ten) | PGLYRP-2 | CAG06114 | - | - | - | Predicted amidase |
Amphibians | Â | Â | Â | Â | Â | Â |
Xenopus laevis, African clawed frog (Xl) | PGLYRP-5 | BC087429 | 496035 | - | - | Predicted amidase |
Xenopus tropicalis, Western clawed frog (Xt) | PGLYRP-1 | NM_001030455 | 595014 | - | - | Predicted amidase |
 | PGLYRP-5 | NM_001015775 | 548492 | - | - | Predicted amidase |
Birds | Â | Â | Â | Â | Â | Â |
Gallus gallus, chicken (Gg) | PGLYRP-2 | AY740510 | - | - | - | Predicted amidase |
Mammals | Â | Â | Â | Â | Â | Â |
Bos taurus, cow (Bt) | PGLYRP-1 | NM_174573 | 282305 | 18 | - | Bactericidal [46,47] |
 | PGLYRP-2 | XM_588006 | 510803 | 7 | - | Predicted amidase |
 | PGLYRP-3 | XM_611696 | 532575 | 3 | - | Predicted bactericidal¥ |
Camelus dromedaries, camel (Cd) | PGLYRP-1 | AJ409286 | - | - | - | Predicted bactericidal |
Canis familiaris, dog (Cf) | PGLYRP-1 | XM_849945 | 612209 | 1 | - | Predicted bactericidal |
 | PGLYRP-2 | XM_847906 | 610405 | 20 | - | Predicted amidase |
Homo sapiens, human (Hs) | PGLYRP-1 | NM_005091 | 8993 | 19q13.2-q13.3 | 1YCK | Bactericidal [17] |
 | PGLYRP-2 | NM_052890 | 114770 | 19p13.12 | - | Amidase [9,16] |
 | PGLYRP-3 | NM_052891 | 114771 | 1q21 | 1SK3, 1SK4, 1TWQ, 2APH | Bactericidal [17] |
 | PGLYRP-4 | NM_020393 | 57115 | 1q21 | - | Bactericidal [17] |
Mus musculus, mouse (Mm) | PGLYRP-1 | NM_009402 | 21946 | 7 A3 | - | Antibacterial [45,48] |
 | PGLYRP-2 | AY282722 | 57757 | 17 | - | Amidase [15] |
 | PGLYRP-3 | NM_207247 | 242100 | 3 F1 | - | Predicted bactericidal |
 | PGLYRP-4 | NM_207263 | 384997 | 3 F1 | - | Predicted bactericidal |
Pan troglodytes, chimpanzee (Pt) | PGLYRP-2 | XM_512455 | 455797 | 19 | - | Predicted amidase |
Rattus norvegicus, rat (Rn) | PGLYRP-1 | NM_053373 | 84387 | 1q21 | - | Predicted bactericidal |
 | PGLYRP-2 | BC088306 | 299567 | 7q11 | - | Predicted amidase |
 | PGLYRP-3 | XM_57498 | 499658 | 2q34 | - | Predicted bactericidal |
 | PGLYRP-4 | XM_227383 | 310611 | 2q34 | - | Predicted bactericidal |
Sus scrofa, pig (Ss) | PGLYRP-1 | NM_001001260 | 397213 | - | - | Predicted bactericidal |
 | PGLYRP-2A | AF541955 | - | - | - | Amidase [44] |
 | PGLYRP-2B | AF541956 | - | - | - | Amidase [44] |