From: Co-evolution of transcription factors and their targets depends on mode of regulation
TF type | In E. coli K12 | Entero-absent* | Entero- present† | Widely present‡ |
---|---|---|---|---|
All TFs | 143 | 65 (45.5%) | 65 (45.5%) | 13 (9%) |
TFs that regulate ≤ 5 targets | ||||
All | 71 | 34 (48%) | 35 (49%) | 2 (3%) |
Activators | 39 | 22 (56%) | 16 (41%) | 1 (3%) |
Repressors | 27 | 11 (41%) | 15 (56%) | 1 (3%) |
Dual regulators | 5 | 1 (20%) | 4 (80%) | 0 (0%) |
TFs that regulate >5 targets | ||||
All | 72 | 31 (43%) | 30 (42%) | 11 (15%) |
Activators§ | 29 | 21 (72%) | 7 (24%) | 1 (4%) |
Repressors¶ | 22 | 7 (32%) | 13 (59%) | 2 (9%) |
Dual regulators¥ | 21 | 3 (14%) | 10 (48%) | 8 (38%) |