Figure 2 From: A class of human exons with predicted distant branch points revealed by analysis of AG dinucleotide exclusion zones Distribution of dinucleotide exclusion zones. Shown is the distribution of dinucleotide exclusion zones (mod-EZ) upstream of 49,876 human exons (having excluded cases in which the intron was less that 350 nucleotides). Y-axis: log [number of exons]. X-axis: log [size of mod-EZ]. Data are normalized to give a probability density function, which gives the probability that an exon chosen at random will have an exclusion zone of a given size; the area under each curve is 1. Blue lines: first exclusion zone (mod-EZ1), measured from -25 (relative to the 3' splice site) to the first upstream occurrence of the particular dinucleotide (see Materials and methods). Red lines: second exclusion zone (mod-EZ2), measured from -25 relative to the end of the mod-EZ1. AG shows the largest variance between mod-EZ1 and mod-EZ2. Data was sorted into bins of logarithmically increasing widths rendered discrete (bin width 10 at ~100; bin width 100 at ~1,000), with final bin counts divided by bin width and by the total number of exons, followed by application of a three-point averaging filter to produce the given plots. See Materials and methods for full details.Back to article page