Table 2 RefSeq transcripts with an exon skipping splice form that puts together a new Pfam domain
Gene symbol | Gene name | RefSeq/EST with Pfam* | RefSeq/EST without Pfam†| Pfam ID | Pfam description | Alternative splice event‡ | Pfam cutoff score§ | Score upstream¶ | Score downstream¥ | Score combined# |
|---|---|---|---|---|---|---|---|---|---|---|
na | na | NM_144604 | AK056632 | PF00642 | Zinc finger C-x8-C-x5-C-x3-H type (and similar) | Exon between exon 3 and 4 | 17.5 | -1.2 | 9.4 | 23.6 |
PRSS25 | protease, serine, 25 | NM_145074 | AF141306 | PF00089 | Trypsin | Acceptor upstream of exon 4 | 23.4 | 3.0 | 1.1 | 30.8 |
FOSL2 | FOS-like antigen 2 | NM_005253 | BX647822 | PF00170 | bZIP transcription factor | Acceptor upstream of exon 4 | 23.2 | 16.1 | -4.6 | 31.3 |
na | na | NM_003622 | AB033056 | PF02920 | Integrase_DNA | Exon between exon 8 and 9 | 18.0 | 13.4 | -5.0 | 21.9 |
na | na | NM_006832 | AK091532 | PF00373 | FERM domain (Band 4.1 family) | Exon between exon 12 and 13 | 14.0 | -15.9 | 10.3 | 15.6 |
PQBP1 | Polyglutamine binding protein 1 | NM_144494 | BM692479 | PF00397 | WW domain | Acceptor upstream of exon 3 | 17.0 | 5.0 | 9.7 | 32.5 |
MRPL27 | Mitochondrial ribosomal protein L27 | NM_148570 | BQ028639 | PF01016 | Ribosomal L27 protein | Acceptor upstream of exon 4 | 25.0 | 2.1 | 8.2 | 34.0 |
PLEKHB1 | Pleckstrin homology domain containing, family B (evectins) member 1 | NM_021200 | BE703269 | PF00169 | PH domain | Acceptor upstream of exon 3 | 22.8 | -3.3 | 11.4 | 29.7 |
na | na | NM_020679 | BP265352 | PF02854 | MIF4G domain | Donor downstream of exon 6 | 14.0 | 1.1 | 0.2 | 17.2 |
TRUB2 | TruB pseudouridine (psi) synthase homolog 2 (E. coli) | BE793897 | NM_015679 | PF00849 | RNA pseudouridylate synthase | Skip exon 2 | 14.0 | -2.1 | -1.3 | 14.7 |
na | na | BM903757 | NM_024565 | PF00134 | Cyclin, N-terminal domain | Skip exon 4 | 17.0 | 0.3 | 9.6 | 52.9 |
na | na | BC033491 | NM_139174 | PF00035 | Double-stranded RNA binding motif | Skip exon 2 | 17.0 | -5.2 | 13.5 | 21.7 |